CUREGEN is a test by Genessense that assesses your response to more than 45 drugs and drug classes covering 18 genes across, a range of diseases. The test can tell you whether a medication can be effective for you, whether you need different doses than average and whether you are at risk for serious side effects due to altered metabolism of the medication.
As an example, Asians can be poorer metabolizers of CYP2C19, a prevalent hepatic enzyme that metabolizes at least 10% of all commonly prescribed drugs.
Asians also may need different doses of SSRI antidepressants, cancer drugs and many others, for the same reasons.
This results in reduced activity of drugs like clopidogrel, with Asians being at higher risk of adverse effects from this drug such as heart attack and stroke.
The adverse events can range from those related to altered drug efficacy to severe skin reactions. Pharmacogenomic testing for this variant can reduce these risks. Read on for more.
Source: https://ascpt.onlinelibrary.wiley.com/doi/full/10.1111/cts.12771
Genessense follows the latest guidelines prescribed by the Clinical Pharmacogenetics Implementation Consortium (CPIC) and PharmGKB covering more than 45 drugs and drug classes.
CUREGEN only looks at drugs for which level of evidence is strong as per established guidelines.
We do not cover any drug that does not have sufficient evidence unlike some of our competitors.
We follow guidelines and recommendations made by
*https://www.cdc.gov/medicationsafety/adult_adversedrugevents.html
