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Genetic risk assessment for Hypercholesterolemia

What is Lipidgen Screening?

Lipidgen is a genetic screening that helps to estimate the genetic predisposition of an individual to develop hypercholesterolemia with the help of polygenic risk score (PRS). The risk is calculated by analysing over 223 genetic markers implicated in the disease and is given as a validated PRS.

Hypercholesterolemia: Is the presence of high blood cholesterol level. High levels of cholesterol in the blood can develop fatty deposits in blood vessels and increase the risk of heart disease, stroke etc.

What is Polygenic Risk Score?

The score indicates if the individual is at high, moderate, or average genetic risk for developing hypercholesterolemia.

The Polygenic Risk Score (PRS) quantifies the contributing effects of multiple genetic (DNA) markers into a score and estimates whether the tested individual is at a high, moderate, or average risk of developing a health condition.

Lipidgen screening is validated for the South Asian population.

Who should take the Lipidgen Screening?

  • Individuals: males above the 45 years of age and females above the 55 years of age.
  • Individuals with the family history of hypercholesterolemia, premature atherosclerotic cardiovascular disease.
  • Individuals with comorbidities like hypertension and diabetes.
  • Individuals with habits like smoking and excessive alcohol consumption.
  • Individuals above the age of 18 years.

How will Lipidgen help you?

Knowing the genetic risk for hypercholesterolemia by Lipidgen will help one to take informed decisions towards leading a healthy life. This screening test is extremely helpful to identify the probable condition thus avoiding your disease progression resulting in complications, trauma, and treatments.

Lipidgen report provides scientific recommendations which can help in taking preventive measures to mitigate the disease risk. The recommendations include lifestyle changes like engaging in physical activity, balanced and healthy diet, health monitoring by routine health checkup, enhanced screening, and scientific evidence on benefits of knowing genetic risk for a health condition.

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